Diabetes is a long-term disease characterised by high blood glucose (sugar) levels that occur when:
The pancreas does not produce enough insulin1 and/or when the body cannot effectively use the insulin it produces to move glucose into the cells of the body as a source of energy (insulin resistance = cells become resistant to the effects of insulin)2
Diabetes has reached epidemic proportions and its prevalence continues to grow worldwide. By 2014 WHO (World Health Organization) estimated that, globally, 422 million adults over 18 years of age were living with diabetes.3
Type 2 Diabetes Mellitus (T2DM) is the most common form of Diabetes and accounts for up to 90% of all cases. T2DM is a considered a progressive lifestyle disease caused mainly by a poor diet and lack of exercise although some people are genetically at a higher risk of developing it. This informational leaflet focusses on T2DM.1,3,7
Gestational diabetes is a raised blood glucose level during pregnancy which occurs in some women. However blood glucose levels usually return to normal levels shortly after delivery.3
Prediabetes is the grey area before developing T2DM in which:
Signs and symptoms are not yet profoundly visible but your blood glucose levels are starting to elevate beyond what is considered healthy.
Prediabetes is a state in which following poor lifestyle choices your body’s cells may, over time, become less responsive to the insulin it produces. This is known as insulin resistance. In this state, your body requires and produces more and more insulin to maintain healthy blood glucose levels resulting in a state of hyperinsulinemia (raised insulin levels). Although still within normal ranges your blood glucose readings may start to elevate over a period of time due to:
The progressive nature of the disease and because your body is no longer able to keep up production of insulin with the body’s ever-increasing requirement
Ignoring the early warning signs and risk factors could lead to the development of T2DM.
The risk factors for developing T2DM include:
Your doctor takes a thorough medical history and you have a general medical examination. If they suspect T2DM, laboratory tests are performed to evaluate your blood glucose levels. At least two glucose tests are required and ideally should be performed on two separate days. A fasting blood glucose reading of ≥7 mmol/l, a random blood glucose level of ≥11 mmol/l, or a two-hour post glucose ingestion reading of ≥ 11 mmol/l is required for diabetes to be confirmed. An HbA1c (this test shows the average blood glucose levels over 3 months) level of ≥6,5% is also adequate to confirm the diagnosis.
Once the T2DM diagnosis is confirmed, treatment will commence and will consist of a combination of lifestyle changes and medical intervention.
Useful tips and what to expect: